Atg7 Deficiency Intensifies Inflammasome Activation and Pyroptosis inPseudomonasSepsis
نویسندگان
چکیده
منابع مشابه
Subversion of inflammasome activation and pyroptosis by pathogenic bacteria
Activation of the inflammasome occurs in response to a notably high number of pathogenic microbes and is a broad innate immune response that effectively contributes to restriction of pathogen replication and generation of adaptive immunity. Activation of these platforms leads to caspase-1- and/or caspase-11-dependent secretion of proteins, including cytokines, and induction of a specific form o...
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ژورنال
عنوان ژورنال: The Journal of Immunology
سال: 2017
ISSN: 0022-1767,1550-6606
DOI: 10.4049/jimmunol.1601196